[IF: 5.682 (JCR2020), ERICA 상위 8.302%] Sus1 maintains a normal lifespan through regulation of TREX-2 complex-mediated mRNA export.

Suji Lim*, Yan Liu*, Byung-Ho Rhie, Chun Kim, Hong-Yeoul Ryu‡, Seong Hoon Ahn‡

* Equal contribution

‡Jointly supervised the study.

Aging-US. 2022 Jun 29;14(12): 4990—5012 (ISSN: 1945-4589)

[IF: 5.924 (JCR2020), ERICA 상위 11.844%] Nuclear mRNA Export and Aging.

Park HS, Lee JB, Lee HS, Ahn SH‡ and Ryu HY‡

‡ These authors jointly supervised.

Int J Mol Sci. 2022 May 13;23(10), 5451. (ISSN 1422-0067)

[IF: 4.556 (JCR2019), ERICA 상위 13.431%] Epigenetic Targeting of Histone Deacetylases in Diagnostics and Treatment of Depression.

Park HS, Kim J, Ahn SH and Ryu HY

Int J Mol Sci. 2021 May 20;22(10):5398. (ISSN 1422-0067)

[IF: 5.432 (JCR2020), ERICA 상위 15.096%] The Spt7 subunit of the SAGA complex is required for the regulation of lifespan in both dividing and nondividing yeast cells.

Lim S, Ahn HJ, Duan R, Liu Y, Ryu HY, Ahn SH

Mech Ageing Dev. 2021 Apr 5;196:111480. Online ahead of print (ISSN 0047-6374)

[IF: 7.69 (JCR2020), ERICA 상위 7.05%] SUMO and cellular adaptive mechanisms.

Ryu HY, Ahn SH, Hochstrasser M.

Exp Mol Med. 2020 Jun;52(6):931-939. Epub 2020 Jun 26 (ISSN: 1226-3613)

[IF: 3.992 (JCR2020), ERICA 상위 29.8%] Symmetric dimethylation on histone H4R3 associates with histone deacetylation to maintain properly polarized cell growth. 

Duan R, Ryu HY, Ahn SH.

Res Microbiol. 2020 Mar 171(2):91-98. Epub 2019 Sep 28 (ISSN: 0923-2508)

[IF: 9.261 (JCR2020), ERICA 상위4.9%] Multiple roles of CTDK‑I throughout the cell.

Srivastava R*, Duan R*, Ahn SH. 

Cell Mol Life Sci. 2019 Jul;76(14):2789-2797. Epub 2019 Apr 29 (ISSN: 1420-682X) (*Co-1st author)

[IF: 3.992 (JCR2020), ERICA 상위 29.8%] Yeast symmetric arginine methyltransferase Hsl7 has a repressive role in transcription. 

Ryu HY*, Duan R*, Ahn SH.

Res Microbiol. 2019 Jun - Aug;170(4-5):222-229. Epub 2019 Jan 17 (ISSN: 0923-2508) (*Co-1st author)

[IF: 12.568 (JCR2019) ERICA 상위 1.3%] The Epigenetic Pathways to Ribosomal DNA Silencing.

Srivastava, R., Srivastava, R., Ahn, SH.

Microbiol Mol Biol Rev. 2016 Jun 1;80(3):545-63 (ISSN: 1092-2172, Issues/Year: 4) (Print 2016 Sep.)

[IF: 10.744 (JCR2019), ERICA 상위 3.8%] Modifications of RNA polymerase II CTD: Connections to the histone code and cellular function.

Srivastava R, Ahn SH.

Biotechnol Adv. 2015 Nov 1;33(6 Pt 1):856-72 (ISSN: 0734-9750)

[IF = 7.984, ERICA 상위 7.3%] Yeast histone H3 lysine 4 demethylase Jhd2 regulates mitotic rDNA condensation.

Ryu HY, Ahn SH.

BMC Biol. 2014 Sep 24;12(1):75 (ISSN: 1741-7007)

[IF = 2.484] Loss of the Set2 histone methyltransferase increases cellular lifespan in yeast cells.

Ryu HY, Rhie BH, Ahn SH.

Biochem Biophys Res Commun. 2014 Mar 28 446(1):113–118 (Weekly ISSN: 0006-291X)


[IF = 0.565] The yeast ESCRT complexes are involved in the regulation of transcription elongation.

Song YH, Duan R, Ryu HY, Ahn SH.

Genes Genom 2014 June 36(3):335–343 (Bimonthly ISSN: 1976-9571)

[IF = 2.484] The RNA polymerase II Rpb4/7 subcomplex regulates cellular lifespan through an mRNA decay process.

Duan R, Rhie BH, Ryu HY, Ahn SH.

Biochem Biophys Res Commun. 2013 Nov 8 441(1):266-270. 

[IF = 2.484] Cellular aging is associated with increased ubiquitylation of histone H2B in yeast telomeric heterochromatin.

Rhie BH, Song YH, Ryu HY, Ahn SH.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):570-575. Epub 2013 Sep 8.

[IF = 0.841] A Fermented Ginseng Extract, BST204, Inhibits Proliferation and Motility of Human Colon Cancer Cells.

Park JW, Lee JC, Ann S, Seo DW, Choi WS, Yoo YH, Park SK, Choi JY, Um SH, Ahn SH and Han JW.

Biomolecules & Therapeutics. 2011 Apr 19 (2) 211-217 (ISSN: 1976-9148)

[IF = 2.648] Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions.

Kwon DW, Ahn SH.

Biochem Biophys Res Commun. 2011 Jul 8;410(3):614-9. Epub 2011 Jun 12.

[IF = 2.648] IMP dehydrogenase is recruited to the transcription complex through serine 2 phosphorylation of RNA polymerase II.

Park JH, Ahn SH.

Biochem Biophys Res Commun. 2010 Feb 19;392(4):588-592.

[IF = 5.520] A Bre1-associated Protein, Large 1 (Lge1), Promotes H2B Ubiquitylation during the Early Stages of Transcription Elongation.

Song YH, Ahn SH.

J Biol Chem. 2010 Jan 22;285(4):2361-7 (ISSN: 0021-9258)

[IF = 1.765] A Novel γ-Lactam-Based Histone Deacetylase Inhibitor Potently Inhibits the Growth of Human Breast and Renal Cancer Cells.

Kwon HK*, Ahn SH*, Park SH, Park JH, Park JW, Kim HM, Park SK, Lee K, Lee CW, Choi E, Han G and Han JW.

Biol Pharm Bull. 2009 Oct 3;32(10) 1723-1727.

*Equally contributed 1st authors

[IF = 1.765] Rapamycin Down-Regulates Inducible Nitric Oxide Synthase by Inducing Proteasomal Degradation.

Jin HK*, Ahn SH*, Yoon JW, Park JW, Lee EK, Yoo JS, Lee JC, Choi WS, Han JW.

Biol Pharm Bull. 2009 Jun;32(6):988-92.

*Equally contributed 1st authors

[IF = 8.295] Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II.

Ahn SH*, Keogh MC, Buratowski S.

EMBO J. 2009 Feb 4;28(3):205-12. Epub 2009 Jan 8.

*Corresponding  author. This paper has been selected for Faculty of 1000 Biology evaluated by Francesc Posas.

[IF = 5.520] Reversine Increases the Plasticity of Lineage-committed Cells toward Neuroectodermal Lineage.

Lee EK, Bae GU, You JS, Lee JC, Jeon YJ, Park JW, Park JH, Ahn SH, Kim YK, Choi WS, Kang JS, Han G, Han JW.

J Biol Chem. 2009 Jan 30;284(5):2891-901. Epub 2008 Nov 17.

[IF = 7.216] Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells.

You JS, Kang JK, Lee EK, Lee JC, Lee SH, Jeon YJ, Koh DH, Ahn SH, Seo DW, Lee HY, Cho EJ, Han JW.

Oncogene. 2008 Feb 28;27(10):1376-86. Epub 2007 Sep 10.

[IF = 1.847] Suppression of the NF-kappaB signalling pathway by ergolide, sesquiterpene lactone, in HeLa cells.

Chun JK, Seo DW, Ahn SH, Park JH, You JS, Lee CH, Lee JC, Kim YK, Han JW.

J Pharm Pharmacol. 2007 Apr;59(4):561-6.

[IF = 2.648] PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells.

Eun DW*, Ahn SH*, You JS, Park JW, Lee EK, Lee HN, Kang GM, Lee JC, Choi WS, Seo DW, Han JW.

Biochem Biophys Res Commun. 2007 Mar 16;354(3):769-75. Epub 2007 Jan 17.

*Equally contributed 1st authors

[IF = 2.648] Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites.

Kim S, Kang JK, Kim YK, Seo DW, Ahn SH, Lee JC, Lee CH, You JS, Cho EJ, Lee HW, Han JW.

Biochem Biophys Res Commun. 2006 Apr 21;342(4):1168-73. Epub 2006 Feb 23.

[IF = 31.253] Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ.

Cell. 2005 Nov 18;123(4):593-605.

[IF = 8.295] Transitions in RNA polymerase II elongation complexes at the 3' ends of genes.

Kim M, Ahn SH, Krogan NJ, Greenblatt JF, Buratowski S.

EMBO J. 2004 Jan 28;23(2):354-64. Epub 2004 Jan 22.

[IF = 12.903] Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing.

Ahn SH, Kim M, Buratowski S.

Mol Cell. 2004 Jan 16;13(1):67-76.

[IF = 5.942] RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

Krogan NJ, Kim M, Ahn SH, Zhong G, Kobor MS, Cagney G, Emili A, Shilatifard A, Buratowski S, Greenblatt JF.

Mol Cell Biol. 2002 Oct;22(20):6979-92.

[IF = 5.520] Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells.

Kwon SH, Ahn SH, Kim YK, Bae GU, Yoon JW, Hong S, Lee HY, Lee YW, Lee HW, Han JW.

J Biol Chem. 2002 Jan 18;277(3):2073-80. Epub 2001 Nov 6.

[IF = 2.021] Purification and characterization of protein methylase II from Helicobacter pylori.

Kim YM, Ahn SH, Seo DW, Kim YK, Han JW, Hong S, Kim S, Paik WK, Lee HW.

FEMS Microbiol Lett. 2001 Feb 5;195(1):53-8.

[IF = 5.520] Activation of p21(WAF1/Cip1) transcription through Sp1 sites by histone deacetylase inhibitor apicidin: involvement of protein kinase C.

Han JW*, Ahn SH*, Kim YK, Bae GU, Yoon JW, Hong S, Lee HY, Lee YW, Lee HW.

J Biol Chem. 2001 Nov 9;276(45):42084-90. Epub 2001 Sep 10.

*Equally contributed 1st authors

[IF = 8.460] Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.

Han JW*, Ahn SH*, Park SH, Wang SY, Bae GU, Seo DW, Kwon HK, Hong S, Lee HY, Lee YW, Lee HW.

Cancer Res. 2000 Nov 1;60(21):6068-74.

*Equally contributed 1st authors

[IF = 1.074] NO/cGMP pathway is involved in exocrine secretion from rat pancreatic acinar cells.

Ahn SH, Seo DW, Ko YK, Sung DS, Bae GU, Yoon JW, Hong SY, Han JW, Lee HW.

Arch Pharm Res. 1998 Dec;21(6):657-63.

[IF = 1.074] Changes of nitric oxide synthase activity and free methylarginines contents in regenerating rat liver after partial hepatectomy.

Lee YJ, Nam SW, Seo DW, Ahn SH, Ko YK, Sung DS, Han JW, Hong SY, Lee HW.

Arch Pharm Res. 1997 Jun;20(3):239-46

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